文章摘要
基于数据挖掘《景岳全书·妇人规》治疗崩漏的用药规律
Data mining based on the medication rules of Jingyue Quanshu·Furen Gui for the treatment of metrorrhagia and metrostaxis
DOI:
中文关键词: 《景岳全书·妇人规》  崩漏  数据挖掘  用药规律
英文关键词: Jingyue Quanshu·Furen Gui  metrorrhagia and metrostaxis  Data mining  Medication rules
基金项目:湖北省中医药管理局中医药重点项目
作者单位邮编
董泳琪 湖北中医药大学 430061
黄晓桃* 湖北中医药大学华中科技大学同济医学院附属湖北省妇幼保健院中西医结合科 
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中文摘要:
      目的:运用数据挖掘分析《景岳全书·妇人规》治疗崩漏的用药规律。方法:筛选《妇人规》中治疗崩漏的方剂,采用频数统计、关联规则、聚类分析等技术挖掘其治疗崩漏的用药规律。结果:共得到方剂52首,涉及中药85味,总累计频次346次。常用中药有人参、炙甘草、当归等;以补虚药、收涩药等为主;药性偏寒;药味以甘、苦、辛为主;归经以肝经、脾经居多;关联规则分析得到24组核心药对;聚类分析得到4首新处方。结论:研究运用现代统计学方法对《妇人规》治疗崩漏的方剂进行数据挖掘,可以看出张景岳治疗崩漏时遣方用药特色鲜明,可为现代临床治疗用药提供借鉴。但本研究对崩漏的药物组方分析与挖掘有限,需要更进一步地研究。
英文摘要:
      Objective To analyze the medication pattern of”Jingyue Quanshu·Furen Gui" for treating metrorrhagia and metrostaxis using data mining. Methods Screening the formulas for treating metrorrhagia and metrostaxis in"Furen Gui", and mining their medication patterns for treating metrorrhagia and metrostaxis using frequency statistics, association rules, cluster analysis and other techniques. Results A total of 52 formulas were obtained, involving 85 flavors of traditional Chinese medicine, with a total cumulative frequency of 346 times. Commonly used Chinese medicines included ginseng, radix glycyrrhizae preparata, angelica, etc; the main medicines were deficiency tonic and astringent, etc;the medicinal properties of the medicines were cold;the medicinal flavors were mainly sweet, bitter,and pungent;and the attributed meridians were mostly the liver meridian and the spleen meridian;the analysis of the association rules yielded 24 groups of core medicinal pairs;and the clustering analysis yielded 4 new formulas. Conclusion The study utilized modern statistical methods to mine the data of the prescriptions of "Furen Gui"for the treatment of metrorrhagia and metrostaxis, and it can be seen that Zhang Jingyue has distinctive features in the treatment of metrorrhagia and metrostaxis, which can be used as a reference for the use of medicines in modern clinical treatment. However, this study is limited in analyzing and mining the drug formulas for metrorrhagia and metrostaxis, and further research is needed.
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