文章摘要
参芪地黄汤联合连续性血液净化用于急性肾损伤患者治疗临床症状及炎症反应改善作用研究
Effect of Shenqidihuang decoction combined with continuous blood purification on clinical symptoms and inflammatory response in patients with acute kidney injury
DOI:
中文关键词: 急性肾损伤  联合治疗  参芪地黄汤  连续性血液净化  炎症反应  临床症状
英文关键词: acute kidney injury  combined treatment  Shenqi Dihuang decoction  continuous blood purification  inflammatory reaction  clinical symptoms
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作者单位邮编
梅丽* 信阳市中医院 464000
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中文摘要:
      【】目的:探讨参芪地黄汤联合连续性血液净化治疗急性肾损伤的效果及对临床症状与炎症反应的改善作用。方法:纳入信阳市中医院肾内科2023年1月至2024年12月收治的90例急性肾损伤患者作为研究对象,采用随机数字表法将其均等分配至对照组与观察组进行临床对照分析,每组45例。给予对照组连续性血液净化治疗,观察组参芪地黄汤与连续性血液净化联合治疗。比较两组治疗前后的临床症状变化、炎症反应、治疗有效率及肾功能恢复情况等。结果:治疗结束后发现,观察组临床症状积分、炎症反应指标CRP、TNF-α、IL-8水平及肾功能指标Scr、BUN、ET水平均低于对照组 (P<0.05),观察组治疗总有效率(93.33%)高于对照组(80.00%)(P<0.05)。结论:参芪地黄汤与连续性血液净化联合治疗,不仅有效改善急性肾损伤患者的临床症状,减轻炎症反应,还能促进肾功能恢复,进一步提高临床治疗效果。
英文摘要:
      Objective: to investigate the effect of Shenqi Dihuang decoction combined with continuous blood purification on acute kidney injury (Aki) and its improvement of clinical symptoms and inflammatory response. Methods: a total of 90 patients with Aki 2023 from January to December 2024 in the Department of Nephrology, Xinyang Hospital of traditional Chinese medicine were enrolled in this study, the random number table method was used to equally allocate them to the control group and the Observation Group for clinical control analysis, 45 cases in each group. The control group was treated with continuous blood purification, and the observation group was treated with Shenqi Dihuang decoction and continuous blood purification. The changes of clinical symptoms, inflammatory reaction, effective rate and recovery of renal function were compared between the two groups before and after treatment. Results: after treatment, the clinical symptom score, inflammatory reaction index CRP, TNF-α, IL-8 levels and renal function index SCR, Bun, ET levels in the observation group were lower than those in the control group (p < 0.05) , the total effective rate of observation group (93.33%) was higher than that of control group (80.00%)(p < 0.05) . Conclusion: Shenqi Dihuang decoction combined with continuous blood purification can not only effectively improve the clinical symptoms of patients with acute kidney injury, reduce the inflammatory reaction, but also promote the recovery of renal function and further improve the clinical treatment effect.
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