| 基于古今医案云平台的近视中医药内外治法发现:161则医案用药与取穴规律分析 |
| Discovery of Internal and External TCM Treatments for Myopia Based on the Ancient and Modern Medical Case Cloud Platform: An Analysis of Drug Use and Acupoint Selection Patterns in 161 CasesJinyan Wang1,Ziyun Zeng2, Qingyuan Ji2,Feiyang Long1,Yifei Ye2, Sirui Chen3,Fuyue Lu3,Qinqin Zhou2,Bingxue Liang1* |
| DOI： |
| 中文关键词: 近视 能近怯远 中医药 古今医案云平台 穴位配伍 |
| 英文关键词: Myopia Capable of seeing near but fearful of distant vision Traditional Chinese Medicine (TCM) Ancient and Modern Medical Cases Cloud Platform Acupoint combination |
| 基金项目:重庆中医药学院“三栖名师”能力提升项目SQMS2024QNXM-18；重庆市教育委员会科学技术研究项目KJQN202215106, KJQN202315121；重庆市2025年大学生创新训练计划项目S202514830003 |
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| 中文摘要: |
| 目的 通过数据挖掘技术，系统性揭示中医药内外治法治疗近视的核心穴位配伍、中药药性规律及‘局部-远端’取穴模式，为临床方案优化提供循证依据。方法 收集并整理关于中医药内外治法治疗近视的有效医案。利用古今医案云平台对医案数据进行清洗、标准化处理。采用频次分析、关联规则挖掘等方法，对治疗近视所用中药的归经、五味、常用药物以及穴位的核心组合与配伍规律进行深入的数据挖掘与统计分析。结果 本研究基于数据挖掘技术，采集医方医案共计161篇，药物总个数173个，总频次710次，穴位总个数14个，总频次569次。清晰地揭示了中医药外治近视的组方与选穴规律。药物分析显示，治疗近视的中药主要归属于肝经（41.63%）、脾经（27.85%）和肺经（26.3%）；药味以甘味（44.3%）、苦味（28.27%）和辛味（23.77%）为主。常用核心中药包括菊花、当归、黄芪、党参、枸杞子等。穴位分析发现，眼周局部穴位如攒竹、太阳、鱼腰、睛明、四白等是治疗核心。关联规则挖掘揭示了高频配伍组合，如“攒竹-太阳”（支持度0.25）、“攒竹-鱼腰（支持度0.24）、“丝竹空-攒竹”（支持度0.24）等。同时，发现“光明-风池”（提升度2.88）等远端穴位与局部穴位结合的配伍模式，体现了局部辨证与整体调节相结合的治疗思路。结论 治疗上注重疏肝明目、健脾益气；选穴策略上强调以眼周局部穴位为核心，并结合远端循经取穴进行整体调理。研究结果为近视的中医药外治提供了客观的证据支持，对优化临床治疗方案具有重要的参考价值。 |
| 英文摘要: |
| Objective Through data mining techniques, the core acupoint compatibility, patterns of Chinese materia medica properties, and the "local-distal" acupoint selection paradigm in Traditional Chinese Medicine (TCM) internal and external therapeutics for myopia, thereby providing an evidence-based foundation for clinical protocol optimization.Methods Effective medical cases on internal and external TCM treatment of myopia were collected and organized. The data were cleaned and standardized using the Ancient and Modern Medical Case Cloud Platform. Frequency analysis and association rule mining methods were applied to deeply analyze the meridian tropism, five flavors, commonly used herbs, core acupoint combinations, and compatibility patterns involved in myopia treatment.Results Based on data mining methodologies, this study analyzed 161 traditional Chinese medical prescriptions and clinical cases, encompassing 173 herbal components with a cumulative frequency of 710 occurrences, and 14 acupoints with a cumulative frequency of 569 occurrences, thereby elucidating the underlying principles of herbal formulation and acupoint selection in the external treatment of myopia.Herbal analysis showed that the medicines used to treat myopia primarily belonged to the liver meridian (41.63%), spleen meridian (27.85%), and lung meridian (26.3%). The predominant flavors were sweet (44.3%), bitter (28.27%), and pungent (23.77%). Commonly used core herbs included Chrysanthemum, Angelica sinensis, Astragalus membranaceus, Codonopsis pilosula, and Lycium barbarum. Acupoint analysis identified periocular points such as Cuanzhu, Taiyang, Yuyao, Jingming, and Sibai as core treatment sites. Association rule mining revealed high-frequency combinations like “Cuanzhu–Taiyang” (support 0.25), “Cuanzhu–Yuyao” (support 0.24), and “Sizhukong–Cuanzhu” (support 0.24). Additionally, distal acupoint combinations such as “Guangming–Fengchi ” (lift 2.88) were identified, reflecting a treatment philosophy that integrates local syndrome differentiation with holistic regulation. Conclusion The treatment emphasizes liver soothing and eye brightening, spleen strengthening, and qi tonification. Acupoint selection prioritizes periocular local points combined with distal meridian points for overall adjustment. |
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