文章摘要
复方斯亚旦生发酊联合七叶姜黄搽剂治疗脾虚湿蕴型脂溢性脱发的疗效
The effect of compound Siyadan hair growth tincture combined with seven-leaf turmeric liniment on seborrheic alopecia of spleen deficiency and dampness
投稿时间:2021-01-04  修订日期:2021-01-04
DOI:
中文关键词: 复方斯亚旦生发酊  七叶姜黄搽剂  脾虚湿蕴  脂溢性脱发  临床疗效
英文关键词: Compound Siyadan Hair Growth Tincture  Aesculus turmeric Liniment  Spleen Deficiency Damp-heat  Seborrheic Alopecia  Clinical Effect
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作者单位邮编
李琴 湖北中医药大学 430000
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中文摘要:
      目的 观察复方斯亚旦生发酊联合七叶姜黄搽剂治疗脾虚湿蕴型脂溢性脱发的临床疗效。方法 将120例脾虚湿蕴型脂溢性脱发的男性患者随机分为A,B和C组,每组40例。给药方式为:A为外用复方斯亚旦生发酊和七叶姜黄搽剂配合内服中药治疗,B组为中药内服,C组为口服非那雄胺加外用米诺地尔酊。观察各组治疗前后各项症状体征(油腻、皮屑、瘙痒、脱发、生发情况)评分,并比较各组临床疗效、不良反应、复发率、综合满意度。结果 三组治疗后症状体征评分与治疗前进行同组间比较,差异具有统计学意义(p <0.05);A组的“治疗后症状体征变化”、“疗效比较”优于B组,且具有统计学意义(P <0.05);“不良反应”和“复发率”之间无显著差异(P> 0.05)。A和C组之间“治疗后症状体征变化”的比较显示,油腻和瘙痒优于C组(P <0.05),而其他三项(脱发,皮屑与生发)无明显差异(P> 0.05);“疗效比较”无显著差异(P> 0.05);C组的“不良反应”、“复发率”高于A组,具有统计学意义(p <0.05)。A组的满意度高于B、C组,有统计学意义(p <0.05)。结论 在治疗脾虚湿蕴型脂溢性脱发中,复方斯亚旦生发酊结合七叶姜黄搽剂具有明显的治疗效果和安全性。
英文摘要:
      【Abstract】Objective To observe the clinical effect of compound Siyadan hair growth tincture combined with Aesculus turmeric liniment in the treatment of seborrheic alopecia due to spleen deficiency and dampness. Methods 120 male patients with seborrheic alopecia due to spleen deficiency and dampness accumulation were randomly divided into groups A, B and C, with 40 cases in each group. The mode of administration is: A is the external use of compound Siartan hair growth tincture and Aesculus turmeric liniment combined with oral Chinese medicine treatment, group B is oral Chinese medicine, and group C is oral finasteride plus external minoxidil tincture. Observe the scores of various symptoms and signs (greasy, dander, itching, hair loss, hair growth) of each group before and after treatment, and compare the clinical efficacy, adverse reactions, recurrence rate, and overall satisfaction of each group. Results The symptoms and signs scores of the three groups after treatment were compared with those before treatment in the same group. The difference was statistically significant (p <0.05); the "changes in symptoms and signs after treatment" and "comparison of efficacy" of group A were better than those of group B, and had Statistical significance (P <0.05); there was no significant difference between "adverse reactions" and "recurrence rate" (P> 0.05). The comparison of "changes in symptoms and signs after treatment" between groups A and C showed that greasiness and itching were better than group C (P <0.05), while the other three items (hair loss, dandruff and hair growth) had no significant difference (P> 0.05) There was no significant difference in "comparison of efficacy" (P>0.05); the "adverse reactions" and "recurrence rate" of group C were higher than those of group A, which were statistically significant (p <0.05). The satisfaction of group A was higher than that of groups B and C, which was statistically significant (p <0.05). Conclusion In the treatment of seborrheic alopecia due to spleen deficiency and dampness accumulation, the compound Siyadan hair growth tincture combined with Aesculus turmeric liniment has obvious therapeutic effect and safety.
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