文章摘要
金羌宣肺解毒合剂治疗新型冠状病毒肺炎的临床研究
Clinical study of Jinqiangxuanfei jiedu mixture in the treatment of COVID-19
投稿时间:2021-01-21  修订日期:2021-04-10
DOI:
中文关键词: 金羌宣肺解毒合剂  新型冠状病毒肺炎  临床研究
英文关键词: Jin Qiang Xuanfei Jiedu Mixture  COVID - 19  Clinical research
基金项目:国家自然科学基金项目(面上项目,重点项目,重大项目)
作者单位邮编
何红霞 华中科技大学同济医学院附属协和医院中西医结合科 430022
朱习文 华中科技大学同济医学院附属协和医院中西医结合科 
范恒 华中科技大学同济医学院附属协和医院中西医结合科 430022
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中文摘要:
      目的:回顾性评价金羌宣肺解毒合剂治疗新型冠状病毒肺炎(COVID-19)轻型及普通型患者的临床疗效,探讨可能的机制。方法:选取2020年1月20日-3月28日武汉协和医院收治的159例COVID-19轻型及普通型患者作为研究对象,根据是否使用金羌宣肺解毒合剂分为基础组60例和联合组99例。基础组根据国家卫生健康委员会制定的《新型冠状病毒肺炎诊疗方案(试行第六版) 》中推荐的西医治疗方案常规治疗,联合组在西医治疗方案基础上加用金羌宣肺解毒合剂,比较两组治疗前后患者的主要临床症状及实验室指标(白细胞、中性粒细胞、CRP及PCT)的改善情况。结果:金羌宣肺解毒合剂联合常规治疗对比于单纯的常规治疗而言,患者症状改善更明显,实验室指标WBC和NE计数更趋近于正常。结论:基础组常规治疗和联合组联合治疗都可以改善COVID-19患者临床症状,降低炎症水平;相对于基础组常规治疗效果而言,加用金羌宣肺解毒合剂联合治疗的联合组取得了更好的临床疗效。
英文摘要:
      Objective: To retrospectively evaluate the clinical efficacy of Jinqiang Xuanfei Jiedu Mixture in the treatment of mild and common patients with COVID-19 (COVID-19), and to explore the possible mechanism.Methods: A total of 159 mild and common patients with COVID-19 admitted to Wuhan Union Medical College Hospital from January 20 to March 28, 2020 were selected as the research objects, and divided into the basic group (n = 60) and the combined group (n = 99) according to whether Jinqiang Xuanfei Jiedu Mixture was used.The basic group received conventional treatment according to the Western medicine treatment plan recommended in the Covid-19 Diagnosis and Treatment Plan (Trial Sixth Edition) formulated by the National Health Commission.Combined group was treated with Jinqiangxuanfei jiedu mixture on the basis of western medicine treatment.The improvement of main clinical symptoms laboratory indicators (white blood cells, neutrophils, CRP and PCT) of patients before and after treatment was compared between the two groups.Results: Compared with the conventional treatment alone, the symptoms of the patients were improved more obviously, and the laboratory indexes WBC and NE were closer to normal.Conclusion: Both conventional treatment in the basal group and combined treatment in the combination group can improve the clinical symptoms and reduce the level of inflammation in COVID-19 patients.Compared with the conventional treatment effect in the basic group, the combined treatment group with Jinqiangxuanfei jiedu mixture achieved better clinical efficacy.
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