文章摘要
基于数据挖掘探讨刘彤鸥治疗复发性流产孕前用药规律
Study on the Pre-pregnancy Medication Rule of Professor Liu Tongou in the Treatment of Recurrent Spontaneous Abortion Based on Data Mining
投稿时间:2021-03-22  修订日期:2021-03-26
DOI:
中文关键词: 复发性流产  用药规律  刘彤鸥教授  数据挖掘
英文关键词: recurrent spontaneous abortion, drug law, Professor Liu Tongou, data mining
基金项目:基于MTS4对MAPK/EPK通路的调控探讨丹萸饮抑制盆腔炎性疾病后遗症机制的研究
作者单位邮编
周玲 湖北中医药大学中医临床学院 430061
刘彤鸥 湖北中医药大学中医临床学院 
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中文摘要:
      目的:运用数据挖掘技术探讨刘彤鸥教授治疗复发性流产(RSA)孕前用药规律。方法:收集湖北省中医院刘彤鸥教授治疗RSA门诊处方,运用关联分析、聚类分析等数据挖掘方法,对其用药规律进行统计分析。结果:根据纳入标准共纳入处方119首,中药140味,中药使用总频次1713次。其中高频出现的药物有菟丝子、白术、丹参、当归、肉苁蓉等,药物性味以甘、温为主,药物归经以肝、肾、脾经为主,常用药对有菟丝子-桑寄生-续断等;聚类分析可分为5类。结论:刘教授治疗复发性流产孕前用药多取甘温之品,注重从肝、脾、肾论治,治疗时以补肾温阳、益气健脾、疏肝解郁、补血活血为主,孕前预培其损,降低再次流产的概率。
英文摘要:
      Objective: To explore the rule of Liu Tongou"s pre-pregnancy medication in the treatment of recurrent spontaneous abortion (RSA) by using data mining technology.Methods: The prescription of Professor Liu Tongou in the outpatient department of Hubei Hospital of Traditional Chinese Medicine for RSA was collected, and the data mining methods such as correlation analysis and cluster analysis were used to analyze the rule of drug use.Results: According to the inclusion criteria, 119 prescriptions, 140 herbs, and 1713 total frequencies of TCM use were included. The high-frequency medicines are Tusizi, Baizhu, Danshen, Danggui, Roucongrong and so on. The medicinal flavor is mainly sweet and warm, while the liver, kidney and spleen meridian are mainly used as the meridians of drugs. Correlation analysis for an update Tusizi-Sangjisheng-Xuduan, etc.;Cluster analysis can be divided into 5 categories.Conclusion: Professor Liu treats recurrent spontaneous abortion by taking sweet and warm medicine before pregnancy, and pays attention to the treatment from liver, spleen and kidney. In the treatment, tonifying kidney and warming yang, tonifying qi and invigorating spleen, soothing liver and relieving depression, tonifying blood and promoting blood circulation are the main methods. Before pregnancy, the damage is pre-cultured to reduce the probability of recurrent abortion.
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