文章摘要
参芪降糖胶囊联合二甲双胍治疗2型糖尿病的临床疗效及对血脂的影响
Clinical Effect of Shenqi Jiangtang Capsule Combined with Metformin on Type 2 Diabetes Mellitus and Its Effect on Blood Lipid
DOI:
中文关键词: 2型糖尿病  参芪降糖胶囊  二甲双胍  血糖  血脂
英文关键词: type 2 diabetes mellitus  Shenqi Jiangtang Capsule  metformin  blood glucose  blood fat
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作者单位邮编
刘平 南平市第二医院 354200
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中文摘要:
      探究参芪降糖胶囊联合二甲双胍治疗2型糖尿病(T2DM)的临床疗效及对血脂的影响。方法:将62例T2DM患者按照随机数字表法分为观察组和对照组各31例。对照组予以二甲双胍治疗,观察组加用参芪降糖胶囊,两组均治疗2个月。比较两组治疗后临床疗效,治疗前后血糖、血脂变化,不良反应。结果:治疗后,观察组总有效率高于对照组(P<0.05);治疗后,两组FPG、2hPG、HbA1c均降低,观察组均低于对照组(P<0.05);治疗后,两组TC、TG、LDL-C均降低,HDL-C均升高,观察组TC、TG、LDL-C均低于对照组(P<0.05),HDL-C高于对照组(P<0.05);两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:参芪降糖胶囊联合二甲双胍治疗T2DM能提高临床疗效,降低血糖,调节血脂,不增加不良反应,值得推广。
英文摘要:
      To explore the clinical effect of Shenqi Jiangtang Capsule Combined with Metformin on type 2 diabetes mellitus (T2DM) and its effect on blood lipids. Methods: 62 patients with T2DM were randomly divided into observation group and control group with 31 cases. The control group was treated with Metformin , and the observation group was treated with Shenqi Jiangtang Capsule on the basis of the control group. They were treated for 2 months. The clinical efficacy of the two groups after treatment, the changes of blood glucose and blood lipid before and after treatment, and the adverse reactions during treatment were compared. Results: After treatment, the total effective rate in the observation group was was higher than the control group (P<0.05); after treatment, FPG, 2hPG and HbA1c in the two groups decreased were lower than before, and the observation group were lower than the control group (P<0.05); After treatment, TC, TG and LDL-C decreased and HDL-C increased in the two groups. TC, TG and LDL-C in the observation group were lower than the control group (P<0.05), and HDL-C was higher than the control group (P<0.05),the difference was not statistically significant(P>0.05). Conclusion: Shenqi Jiangtang Capsule Combined with Metformin in the treatment of T2DM can improve the clinical efficacy, reduce blood glucose, regulate blood lipid and do not increase adverse reactions. It is worthy of popularization.
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