| 2型糖尿病大血管病变的体质分布特点及脂代谢的研究 |
| Study on the constitution distribution characteristics and lipid metabolism of macroangiopaplasia in type 2 diabetes mellitus |
| DOI： |
| 中文关键词: 2型糖尿病 大血管病变 体质 |
| 英文关键词: Type 2 diabetes mellitus Macrovascular disease physical |
| 基金项目:国家自然科学基金(81503572)；山东省自然科学基金(ZR2021MH088) |
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| 中文摘要: |
| 目的：研究2型糖尿病大血管病变患者体质分布特点及脂代谢情况,为防治2型糖尿病大血管病变提供依据。方法：回顾性研究 2021年1月至12月在山东省中医院健康管理中心进行常规体检的140例2型糖尿病患者,根据是否发生大血管病变分为对照组(未发生大血管病变)70例和观察组(合并大血管病变)70例,收集患者的性别、年龄、身体质量指数(BMI)、收缩压(SBP)、舒张压(DBP)、中医体质类型、总胆固醇(TC)、三酰甘油(TG)、高密度脂蛋白胆固醇(HDL-C)、低密度脂蛋白胆固醇(LDL-C)、脂蛋白[Lp(a)]、载脂蛋白B(apo B),运用SPSS26.0进行统计分析。结果：2组血瘀质、平和质分布差异具有统计学意义。观察组的年龄、BMI、TG、LDL-C、Lp(a)、apo B均高于对照组,差异具有统计学意义(P＜0.05),2组之间SBP、DBP、TC、HDL-C差异不具有统计学意义(P＞0.05)。组内比较：LDL-C在观察组不同体质间的分布差异具有统计学意义(P＜0.05)；TC、TG、HDL-C、Lp (a)、apo B在不同体质类型的患者中分布差异不具有统计学意义(P>0.05)。结论：糖尿病大血管病变患者体质类型以血瘀质、阴虚质、痰湿质和气虚质为主,血瘀质是糖尿病大血管病变的易感体质,TG、LDL-C、Lp(a)、apo B等指标与单纯糖尿病比较差异显著,注意调控血瘀质患者的LDL-C,预防、延缓糖尿病大血管事件的发生。 |
| 英文摘要: |
| Objective: To study the characteristics of constitution distribution and lipid metabolism in patients with type 2 diabetic macroangiopaplasia, so as to provide evidence for the prevention and treatment of type 2 diabetic macroangiopaplasia. Methods: A retrospective study was conducted on 140 patients with type 2 diabetes who underwent routine physical examination in Chronic Disease Management Center of Shandong Hospital of Traditional Chinese Medicine from January to December 2021. According to whether macroangiopaplasia occurred, they were divided into control group (without macroangiopaplasia) (70 cases) and observation group (combined with macroangiopaplasia) (70 cases).Gender, age, body mass index (BMI), systolic blood pressure (SBP), diastolic blood pressure (DBP), traditional Chinese medicine constitution type, total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), lipoprotein [Lp (A)] and apolipoprotein B (apo B) were collected, using SPSS26.0 for statistical analysis.Results: There were significant differences in the distribution of blood stasis quality, peace and quality between the two groups.The age, BMI, TG, LDL-C, Lp (A) and apo B of the observation group were higher than those of the control group, and the differences were statistically significant (P < 0.05). There was no significant difference in SBP, DBP, TC and HDL-C between the two groups (P>0.05).Intra-group comparison: the distribution of LDL-C in different bodies of the observation group was statistically significant (P<0.05).There was no significant difference in the distribution of TC, TG, HDL-C, Lp(A) and apoB among patients with different physical types (P>0.05).Conclusion:Diabetic patients with vascular lesions physique type mass with blood stasis, Yin quality, phlegm wet mass and deficiency of mass is given priority to, blood stasis is diabetes vascular lesions of the susceptible, TG, LDL - C, Lp (a) significant difference compared with pure diabetes and apoB index, pay attention to control quality in patients with blood stasis LDL - C, prevent and delay the onset of diabetes vascular events. |
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