| 基于“聚于胃，关于肺”理论探讨调节肠道微生态治疗胃食管反流相关性咳嗽变异性哮喘 |
| Based on the theory of "Stagnant in Stomach and Stopping in Lung", to explore the regulation of intestinal microbiota in the treatment of gastroesophageal reflux-related cough variant asthma |
| DOI： |
| 中文关键词: 咳嗽变异性哮喘 聚于胃,关于肺 胃食管反流 肠道微生态 |
| 英文关键词: cough variant asthma stagnant in stomach and stopping in lung gastroesophageal reflux intestinal microbiome |
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| 中文摘要: |
| 咳嗽变异性哮喘（Cough variant asthma，CVA）属于慢性咳嗽的一种，由于其病情缠绵、容易误诊、临床疗效差的原因，给患者造成了巨大困扰。根据咳嗽变异性哮喘的发病病因，西医认为其与胃食管反流存在密切关系,各种西药对于本病的治疗只是治标不治本，且存在较多药物副作用。中医药在治疗胃食管反流性CVA的诊疗方面具有明显的优势，“聚于胃，关于肺”是总结与肺胃相关咳嗽病因病机的重要思想，研究表明肠道微生态参与了咳嗽变异性哮喘的疾病过程。故本文运用中医理论“聚于胃，关于肺”通过调节肠道微生态探讨胃食管反流相关性咳嗽变异性哮喘的治疗方法。 |
| 英文摘要: |
| "Stagnant in Stomach and Stopping in Lung" is an important theory to summarize the etiology and pathogenesis of cough related to the lungs and stomach, based on pulmonary-gastric associated cough, new ideas for the diagnosis and treatment of gastroesophageal reflux-related cough variant asthma may provide a new way to explore. According to the etiology of cough-variant asthma, Western medicine believes that it is closely related to gastroesophageal reflux. Various western medicines for the treatment of this disease are only a symptom but not a cure, and have more drug side effects. Traditional Chinese medicine (TCM) is an effective means for the treatment of gastroesophageal reflux-related cough variant asthma, but there is no unified understanding at present. Studies have shown that the gut microbiota is involved in the disease process of cough-variant asthma. Traditional Chinese medicine divides this disease into three stages, considering that the disease is located in the lungs and stomach, its pathogenesis is the abnormal distribution of fluid and gas, the principle of treatment is "urgency is to cure the symptoms, and slow is to cure the root cause." Therefore, this article is based on the traditional Chinese medicine theory of "gathering in the stomach, about the lungs", and discusses the etiology and pathogenesis of pulmonary and gastric-related gastroesophageal reflux cough variant asthma and modulating the intestinal microbiota to explore the treatment of gastroesophageal reflux-related cough variant asthma. |
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